A research team at the College of Medicine, University of Basrah, consisting of Prof. Ihsan Idan Al-Simary, Assistant Professor Dr. Essam Muhammad Abdul-Mohsen and Dr. Jassem Muhammad Najm, obtained a patent to enable them to isolate and characterize the exogenous toxins produced by Streptococcus aureus that cause tonsillitis. Where three bacterial toxins produced by Streptococcus pyogenes were discovered, characterized and recorded, and their relationship to causing inflammatory disease or infection of the tonsils in humans was established. The clinical study also showed that all patients suffering from chronic tonsillitis underwent tonsillectomy as a result of the recurrence of tonsillitis more than (four - seven) times a year and because of the recurrence and increase of complications caused by that inflammation such as: high temperature, loss of appetite, difficulty eating and drinking. This leads to the removal of the tonsils, which is the appropriate treatment. Where these toxins were isolated and characterized by relying on international references and centers and using modern molecular techniques, then studying the genetic manifestations and their genetic sequence as being isolated for the first time in such studies as a cause of tonsillitis in its various forms.