Master's thesis at the College of Medicine, University of Basrah discusses the effect of pyridostigmine as an antibotulinum type A: an experimental study on rabbits

Thesis of a master's degree at the College of Medicine, University of Basrah, discussed the effect of pyridostigmine as an antibotulinum type A: an experimental study on rabbits. The research presented by student Huda Salem Qasim aims to assess the toxic effect of botulinum on skeletal muscles and prove the effectiveness of the anticolynsterase pyridostigmine in accelerating spontaneous healing after injecting botulinum toxin into the rabbit model. The research concluded that Botox injections lead to a significant change in the weight of rabbits. Pyridostigmine causes increased weight of rabbit muscles while Botox injections lead to reduced muscle mass. Renal function tests are also significantly improved by Pyridostigmine and worsened  in BOTOX group . Liver function tests are significantly elevated by Pyridostigmine and decreased by BOTOX. Botox injections have increased regulation of AChRs. Pyridostigmine has reduced the regulation of AChRs. Pyridostigmine can act as the most powerful antidot against Botox poisoning. This is the first time this experiment was being conducted in Iraq  that has discussed the antitoxic effect of pyridostigmine against Botox injections