A master's thesis at the College of Medicine, University of Basrah, discussed the impact of different treatment modalities on biomarkers of endothelial dysfunction in patients with type 2 diabetes.  The research presented by the student Muhammad Ali Ismail Jabbar aims to indicate that the biomarker of the vascular endothelium was the focus of research into the effect of different treatment regimens for hypoglycemia on type 2 diabetes. The research concluded that newly diagnosed diabetic patients who were not treated are at risk  To the risk of developing endothelial dysfunction in terms of measuring biomarkers that were low (NOx, GSH) and increased levels (-1ICAM, ENG) pioglitazone appears to have more benefits than other treatment groups for the prevention of endothelial dysfunction by reducing  Blood pressure and glycemic index with the highest NOx level 2SGLT inhibitor treatment had little effect on these biomarkers.